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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name hsa-miR-92b
ncRNA Category miRNA
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line UM samples, plasma
Methods microarray
Expression pattern up-regulated
Functional description miR profiling of tumors by microarray found 6 miRs over-expressed and 19 under-expressed in 33 tumors with monosomy-3 compared to 22 without. Elevated plasma levels in patients with tumor monosomy-3 of miR-92b, identified in the tumor array, and of miR-199-5p and miR-223, identified in the plasma array, were confirmed by quantitative real-time polymerase chain reaction.
PubMed ID 27453764
Year 2016
Title Association of tumor and plasma microRNA expression with tumor monosomy-3 in patients with uveal melanoma.
Drug-related ncRNA NO

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